In this review, he and colleagues focused on studies that were least likely to be biased. Hill retracted his original study and began another analysis, which was published in January 2022. He published the results in July 2021, but later reports found that many of the studies were flawed, and at least one was fraudulent. At the end of 2020, Andrew Hill, MD, a virologist at the University of Liverpool in England, reviewed the results from 23 trials and concluded that the drug could lower the risk of death from COVID-19. Researchers around the world have done small clinical trials to understand whether ivermectin treats COVID-19, the newspaper reported. After receiving reports of people who needed medical attention, particularly after using formulations intended for livestock, the FDA issued a warning that the drug wasn’t approved to be used for COVID-19. Despite the concerns, some doctors began prescribing ivermectin to patients. Laboratory experiments on cells suggested that ivermectin might work, the Times reported.īut some researchers noted that the experiments worked because a high concentration of ivermectin was used, a much higher dose than would be safe for people. At the beginning of the pandemic, researchers checked thousands of existing drugs against the coronavirus to determine if a potential treatment already existed. Ivermectin has become a controversial focal point during the pandemic.įor decades, the drug has been widely used to treat parasitic infections. The researchers found “no important effects” of treatment with ivermectin on the number of days people spent in the hospital, the number of days hospitalized people needed mechanical ventilation, or the risk of death, they wrote. The drug also didn’t help patients recover sooner. But those who took the drug during the first 3 days after a positive coronavirus test ended up doing worse than those in the placebo group. In addition, the researchers looked at particular groups to understand if some patients benefited for some reason, such as taking ivermectin sooner after testing positive for COVID-19. The researchers found that ivermectin didn’t reduce the risk that people with COVID-19 would be hospitalized or go to an emergency room within 28 days after treatment. In the trial, the research team compared more than 1,350 people infected with the coronavirus in Brazil who received either ivermectin or a placebo as treatment.īetween March and August 2021, 679 patients received a daily dose of ivermectin over the course of 3 days. “Now that people can dive into the details and the data, hopefully that will steer the majority of doctors away from ivermectin towards other therapies,” Boulware said. The full data hadn’t been published until now. The researchers shared a summary of the results in August 2021 during an online presentation hosted by the National Institutes of Health. “There’s really no sign of any benefit,” David Boulware, MD, one of the co-authors and an infectious disease specialist at the University of Minnesota, told The New York Times. The findings pretty much rule out the drug as a treatment for COVID-19, the study authors wrote. Ma- Ivermectin, an anti-parasitic drug that became popular as an alternative treatment for COVID-19, showed no signs of quelling the disease or reducing patients’ risk of hospitalization, according to results from a large clinical trial published in The New England Journal of Medicine.
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